منابع مشابه
Induced cortical responses require developmental sensory experience
Sensory areas of the cerebral cortex integrate the sensory inputs with the ongoing activity. We studied how complete absence of auditory experience affects this process in a higher mammal model of complete sensory deprivation, the congenitally deaf cat. Cortical responses were elicited by intracochlear electric stimulation using cochlear implants in adult hearing controls and deaf cats. Additio...
متن کاملSensory experience and cortical rewiring.
Adult primary sensory cortex is not hard wired, but adapts to sensory experience. The cellular basis for cortical plasticity involves a combination of functional and structural changes in cortical neurons and the connections between them. Functional changes such as synaptic strengthening have been the focus of many investigations. However, structural modifications to the connections between neu...
متن کاملSensory experience alters cortical connectivity and synaptic function site specifically.
Neocortical circuitry can alter throughout life with experience. However, the contributions of changes in synaptic strength and modifications in neuronal wiring to experience-dependent plasticity in mature animals remain unclear. We trimmed whiskers of rats and made electrophysiological recordings after whisker cortical maps have developed. Measurements of miniature EPSPs suggested that synapti...
متن کاملCortical Sensory Responses Are Enhanced by the Higher-Order Thalamus.
In the mammalian brain, thalamic signals reach the cortex via two major routes: primary and higher-order thalamocortical pathways. While primary thalamocortical nuclei transmit sensory signals from the periphery, the function of higher-order thalamocortical projections remains enigmatic, in particular their role in sensory processing in the cortex. Here, by optogenetically controlling the thala...
متن کاملEffects of cortical activation on sensory responses in barrel cortex.
Neocortex network activity changes from a deactivated state during quiescence to an activated state during arousal and vigilance. In urethane-anesthetized rats, cortical activation is readily produced by either stimulating the brainstem reticular formation or by application of cholinergic agonists into the thalamus. We studied the effects of cortical activation on spontaneous activity and senso...
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ژورنال
عنوان ژورنال: Brain
سال: 2017
ISSN: 0006-8950,1460-2156
DOI: 10.1093/brain/awx286